Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | BLM | P54132 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 5/20 | 0.59 |
| ▸ | NSD2 | O96028 | 3/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MTOR | P42345 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | FGB | P02675 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 5/20 | 0.51 |
| ▸ | RECQL | P46063 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426702 | 0.92 | TOP2B (0.81) | TOP2BMEN1KMT2ABLMPOLB | |
| SCHEMBL29357976 | 0.92 | TOP2B (0.81) | TOP2BMEN1KMT2ABLMPOLB | |
| SCHEMBL30678386 | 0.88 | MEN1 (0.60) | TOP2BMEN1KMT2ABLMPOLB | |
| SCHEMBL78525 | 0.88 | MEN1 (0.60) | TOP2BMEN1KMT2ABLMPOLB | |
| SCHEMBL29366166 | 0.88 | MEN1 (0.60) | TOP2BMEN1KMT2ABLMPOLB | |
| SCHEMBL29670831 | 0.88 | TOP2B (0.70) | TOP2BMEN1KMT2ABLMPOLB | |
| SCHEMBL23404 | 0.88 | TOP2B (0.70) | TOP2BMEN1KMT2ABLMPOLB | |
| SCHEMBL29374910 | 0.88 | TOP2B (0.70) | TOP2BMEN1KMT2ABLMPOLB | |
| SCHEMBL8947726 | 0.87 | TOP2B (0.74) | TOP2BMEN1KMT2ABLMPOLB | |
| SCHEMBL455300 | 0.86 | TOP2B (0.72) | TOP2BMEN1KMT2ABLMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115056-A | NATURAL AND SYNTHETIC POLYAMIDES | CIBA-GEIGY AG (CH) | 1978-09-19 | — | — | US | disclosed |
| US-4097229-A | Methods for dyeing or printing using amino-anthraquinone reactive disperse dyes | CIBA-GEIGY AG (CH) | 1978-06-27 | — | — | US | disclosed |
| US-4044029-A | Amino-anthraquinone reactive disperse dyes | CIBA-GEIGY AG (CH) | 1977-08-23 | — | — | US | disclosed |