SCHEMBL29670831

SCHEMBL29670831

CNc1ccc(NCCO)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2B Q02880 1/20 0.70
MEN1 O00255 7/20 0.59
KMT2A Q03164 7/20 0.59
BLM P54132 4/20 0.59
POLB P06746 4/20 0.59
NSD2 O96028 3/20 0.59
RXFP1 Q9HBX9 1/20 0.59
RAB9A P51151 4/20 0.55
NPC1 O15118 3/20 0.55
MTOR P42345 2/20 0.55
SIRT2 Q8IXJ6 1/20 0.55
MAPK1 P28482 8/20 0.54
MAPT P10636 8/20 0.54
L3MBTL1 Q9Y468 7/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
TDP1 Q9NUW8 4/20 0.54
EGFR P00533 3/20 0.54
PABPC1 P11940 1/20 0.54
FGB P02675 1/20 0.51
MMP14 P50281 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29374910 1.00 TOP2B (0.70) TOP2BMEN1KMT2ABLMPOLB
SCHEMBL23404 1.00 TOP2B (0.70) TOP2BMEN1KMT2ABLMPOLB
SCHEMBL29357976 0.92 TOP2B (0.81) TOP2BMEN1KMT2ABLMPOLB
SCHEMBL1426702 0.92 TOP2B (0.81) TOP2BMEN1KMT2ABLMPOLB
SCHEMBL20710632 0.91 TOP2B (0.62) TOP2BMEN1KMT2ABLMPOLB
SCHEMBL12588637 0.89 TOP2B (0.58) TOP2BMEN1KMT2ABLMPOLB
SCHEMBL12658889 0.88 TOP2B (0.59) TOP2BMEN1KMT2ABLMPOLB
SCHEMBL11576965 0.88 TOP2B (0.70) TOP2BMEN1KMT2ABLMPOLB
SCHEMBL8947726 0.87 TOP2B (0.74) TOP2BMEN1KMT2ABLMPOLB
SCHEMBL9690761 0.87 MAPT (0.57) TOP2BMEN1KMT2ABLMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4449102-A1 DETECTION SYSTEM FOR THE DETECTION OF (A) CHEMICAL COMPOUND(S) BASED ON DISTINCT PARTICLES IMPREGNATED WITH DISTINCT DETECTION INDICATORS Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2024-10-23 EP disclosed
WO-2023111474-A1 DETECTION SYSTEM FOR THE DETECTION OF (A) CHEMICAL COMPOUND(S) BASED ON DISTINCT PARTICLES IMPREGNATED WITH DISTINCT DETECTION INDICATORS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-06-22 WO disclosed
WO-2023111475-A1 DETECTION SYSTEM SUITABLE FOR USE IN THE DETECTION OF CHEMICAL COMPOUNDS COMPRISING A DETECTION STRIP COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-06-22 WO disclosed
CN-112239911-B Double-sided pile knitted fabric and method for producing dyed yarn 株式会社则武 2022-06-21 CN disclosed