Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | POLB | P06746 | 5/20 | 0.62 |
| ▸ | BLM | P54132 | 4/20 | 0.62 |
| ▸ | NSD2 | O96028 | 3/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MTOR | P42345 | 2/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | FGB | P02675 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357976 | 0.95 | TOP2B (0.81) | TOP2BMEN1KMT2APOLBBLM | |
| SCHEMBL1426702 | 0.95 | TOP2B (0.81) | TOP2BMEN1KMT2APOLBBLM | |
| SCHEMBL455300 | 0.89 | TOP2B (0.72) | TOP2BMEN1KMT2APOLBBLM | |
| SCHEMBL29374910 | 0.87 | TOP2B (0.70) | TOP2BMEN1KMT2APOLBBLM | |
| SCHEMBL8428873 | 0.87 | TOP2B (0.70) | TOP2BMEN1KMT2APOLBBLM | |
| SCHEMBL29670831 | 0.87 | TOP2B (0.70) | TOP2BMEN1KMT2APOLBBLM | |
| SCHEMBL23404 | 0.87 | TOP2B (0.70) | TOP2BMEN1KMT2APOLBBLM | |
| SCHEMBL11576965 | 0.87 | TOP2B (0.70) | TOP2BMEN1KMT2APOLBBLM | |
| SCHEMBL595621 | 0.86 | TOP2B (0.68) | TOP2BMEN1KMT2APOLBBLM | |
| Ametantrone SCHEMBL3344151 | 0.85 | TOP2B (1.00) | TOP2BMEN1KMT2APOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187340-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-8187340-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20110154583-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| US-20110154583-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110154583-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | TOP2B 293/4885MEN1 3187/4885KMT2A 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.