Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 1/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | BLM | P54132 | 4/20 | 0.60 |
| ▸ | NSD2 | O96028 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | FGB | P02675 | 1/20 | 0.60 |
| ▸ | MMP14 | P50281 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375450 | 0.97 | TOP2B (0.71) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL29357976 | 0.93 | TOP2B (0.81) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL1426702 | 0.93 | TOP2B (0.81) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL15271588 | 0.91 | TOP2B (0.73) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL6661577 | 0.89 | CYP19A1 (0.80) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL9883948 | 0.89 | TOP2B (0.62) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL20710632 | 0.89 | TOP2B (0.62) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL8947726 | 0.89 | TOP2B (0.74) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL15271304 | 0.88 | TOP2B (0.83) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL15277979 | 0.88 | TOP2B (0.83) | TOP2BCYP19A1MEN1KMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1039876-B1 | DIRECT HAIR DYE COMPOSITIONS AND METHODS CONTAINING NOVEL ANTHRAQUINONE MIXTURES | P & G CLAIROL INC (US) | 2006-06-07 | — | — | EP | claimed |
| US-5961664-A | THREE 1,4-HYDROXYALKYLAMINO-ANTHRAQUINONE DERIVATIVES, WHEREIN TWO OF THE ANTHRAQUINONE COMPOUNDS IN THE MIXTURE ARE SYMMETRIC AND THE OTHER ANTHRAQUINONE COMPOUND IS ASYMMETRIC, AND WHEREIN EACH OF THE ANTHRAQUINONE COMPOUNDS HAS SIMILAR | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-05 | — | — | US | claimed |
| EP-3229918-B1 | COMPOSITION AND PROCEDURE FOR TREATING KERATINIC FIBERS WITH FLASH EVAPORATION | HENKEL AG & CO KGAA (DE) | 2024-03-13 | — | — | EP | disclosed |
| EP-2515842-B1 | DYEING COMPOSITION COMPRISING A POLYCONDENSATE OF ETHYLENE OXIDE AND PROPYLENE OXIDE | OREAL (FR) | 2020-04-29 | — | — | EP | disclosed |
| US-10342751-B2 | Double-chamber pouch for dyeing human hair | HENKEL AG & CO. KGAA (DE) | 2019-07-09 | — | — | US | disclosed |
| US-20190038534-A1 | COMPOSITION FOR COLOURING HAIR | BEAUTY & BUSINESS S.P.A. (IT) | 2019-02-07 | — | — | US | disclosed |
| US-10179093-B2 | Compositions and methods for coloring keratinic fibers | HENKEL AG & CO. KGAA (DE) | 2019-01-15 | — | — | US | disclosed |
| US-10111508-B2 | Composition and method for treating keratin fibers with flash evaporation | HENKEL AG & CO. KGAA (DE) | 2018-10-30 | — | — | US | disclosed |
| US-10105301-B2 | Composition for colouring hair | BEAUTY & BUSINESS S.P.A. (IT) | 2018-10-23 | — | — | US | disclosed |
| US-20180098927-A1 | DOUBLE-CHAMBER POUCH FOR DYEING HUMAN HAIR | HENKEL AG & CO. KGAA (DE) | 2018-04-12 | — | — | US | disclosed |
| EP-2308455-B1 | Foaming dye II | HENKEL AG & CO KGAA (DE) | 2018-01-03 | — | — | EP | disclosed |
| EP-2301520-A2 | Oxidative dye | Henkel AG & Co. KGaA (DE) | 2011-03-30 | — | — | EP | disclosed |
| WO-2011027077-A2 | COMPOSITION COMPRISING A HYDROPHOBIC DYE, A SPECIFIC MINERAL AND/OR ORGANIC ALKALINE AGENT, A SPECIFIC COMPOUND (I) AND A SPECIFIC ORGANIC COMPOUND (II), AND USE THEREOF IN DYEING | L'OREAL (FR) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011027076-A2 | DYEING METHOD CONSISTING IN APPLYING A METALLIC SALT AND A COMPOSITION CONTAINING A HYDROPHOBIC DYE AND A SPECIFIC COMPOUND | L'OREAL (FR) | 2011-03-10 | — | — | WO | disclosed |
| WO-2010097559-A2 | COMPOSITION CONTAINING A DYE AND 3-PHENYL-1-PROPANOL AND DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010097558-A2 | COMPOSITION CONTAINING A NATURAL OR SYNTHETIC DYE AND AN ALIPHATIC MONOHYDROXYLATED ALCOHOL AND KERATIN FIBRE DYEING METHOD USING SAME | L'OREAL (FR) | 2010-09-02 | — | — | WO | disclosed |
| US-20090282624-A1 | Composition comprising a hydrophobic dye and an alkylene carbonate or a lactone and dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2009-11-19 | — | — | US | disclosed |
| US-20090282624-A1 | Composition comprising a hydrophobic dye and an alkylene carbonate or a lactone and dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2009-11-19 | — | — | US | disclosed |
| EP-2095809-A1 | Composition comprising a hydrophobic colorant and an alkylene carbonate or a lactone and dyeing of keratinous fibres | L'Oréal (FR) | 2009-09-02 | — | — | EP | disclosed |
| US-5961664-A | THREE 1,4-HYDROXYALKYLAMINO-ANTHRAQUINONE DERIVATIVES, WHEREIN TWO OF THE ANTHRAQUINONE COMPOUNDS IN THE MIXTURE ARE SYMMETRIC AND THE OTHER ANTHRAQUINONE COMPOUND IS ASYMMETRIC, AND WHEREIN EACH OF THE ANTHRAQUINONE COMPOUNDS HAS SIMILAR | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10105301-B2 | Composition for colouring hair | TYR, CUTA, COX5B | TOP2B 773/4885CYP19A1 534/4885MEN1 2278/4885 |
| US-20190038534-A1 | COMPOSITION FOR COLOURING HAIR | TYR, CUTA, COX5B | TOP2B 759/4885CYP19A1 537/4885MEN1 2221/4885 |
| US-20090282624-A1 | Composition comprising a hydrophobic dye and an alkylene carbonate or a lactone and dyeing of keratinous fibres | KRT18, H1-0, H1-5 | TOP2B 1869/4885CYP19A1 557/4885MEN1 2019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.