SCHEMBL11577117

SCHEMBL11577117

O=C=NCCCCC(CCCN=C=O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 4/20 0.41
CPN1 P15169 1/20 0.41
FOLH1 Q04609 7/20 0.40
CHRM1 P11229 1/20 0.37
AKR1A1 P14550 1/20 0.37
CHRM3 P20309 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
ADRA1A P35348 1/20 0.37
HRH1 P35367 1/20 0.37
DRD3 P35462 1/20 0.37
SLC6A3 Q01959 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA2 P00918 1/20 0.36
MAPK1 P28482 1/20 0.36
RNPEP Q9H4A4 1/20 0.35
GRIK1 P39086 2/20 0.34
GRIK2 Q13002 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10658816 0.94 FOLH1 (0.39) CPB2CPN1FOLH1CHRM1AKR1A1
SCHEMBL4333917 0.92 FOLH1 (0.41) CPB2CPN1FOLH1CHRM1AKR1A1
SCHEMBL139463 0.87 CPB2 (0.37) CPB2CPN1FOLH1CA2MAPK1
SCHEMBL6392027 0.87 CA2 (0.55) CPB2CPN1CHRM1AKR1A1CHRM3
SCHEMBL12492499 0.84 FOLH1 (0.33) CPB2CPN1FOLH1CHRM1AKR1A1
SCHEMBL12492498 0.78 GSTK1 (0.37) RNPEP
SCHEMBL15158000 0.78 LTA4H (0.46) RNPEPNOS3NOS1NOS2CYP1A2
2-Ethylhexanoic Acid SCHEMBL27628294 0.78 CA2 (0.62) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL110180 0.77 RNPEP (0.33) RNPEPNOS3NOS1NOS2CYP1A2
SCHEMBL8435671 0.77 RNPEP (0.33) RNPEPNOS3NOS1NOS2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012123425-A1 TISSUE ADHESIVE BASED ON PREPOLYMERS CONTAINING ESTER GROUPS BAYER MATERIALSCIENCE AG (DE) 2012-09-20 WO disclosed
US-RE29772-E IMPACT STRENGTH, CLARITY, WEATHER RESISTANCE ROHM AND HAAS COMPANY (US) 1978-09-19 US disclosed