Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037679 | 0.77 | IRAK4 (0.39) | KDM4ETSHRALDH1A1HSD17B10IRAK4 | |
| SCHEMBL5035248 | 0.65 | TSHR (0.53) | CYP3A4THRBTSHRALDH1A1HSD17B10 | |
| SCHEMBL27602591 | 0.64 | EPHX1 (0.50) | KDM4ETHRBTSHRALDH1A1HSD17B10 | |
| SCHEMBL9854650 | 0.64 | TSHR (0.51) | KDM4ECYP3A4THRBTSHRALDH1A1 | |
| SCHEMBL3169558 | 0.64 | THRB (0.53) | CYP3A4THRBTSHRALDH1A1HSD17B10 | |
| SCHEMBL7197042 | 0.64 | KDM4E (0.44) | KDM4ECYP3A4TSHRALDH1A1HSD17B10 | |
| SCHEMBL4553803 | 0.64 | KDM4E (0.44) | KDM4ECYP3A4TSHRALDH1A1HSD17B10 | |
| SCHEMBL6170527 | 0.64 | TP53 (0.42) | KDM4ETSHRALDH1A1HSD17B10IRAK4 | |
| SCHEMBL8038712 | 0.64 | THRB (0.49) | THRBTSHR | |
| SCHEMBL6072932 | 0.64 | TP53 (0.46) | KDM4ETSHRALDH1A1HSD17B10IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067857-A | Polyester catalyst system comprising an antimony-containing polycondensation catalyst and an ethylenically unsaturated compound and process employing same | STAUFFER CHEMICAL COMPANY (US) | 1978-01-10 | — | — | US | disclosed |