Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577262 | 0.77 | KDM4E (0.39) | IRAK4KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL6072932 | 0.72 | TP53 (0.46) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6170527 | 0.72 | TP53 (0.42) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5134567 | 0.71 | KDM4E (0.50) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6171265 | 0.71 | TP53 (0.48) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5598468 | 0.71 | TP53 (0.48) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5598237 | 0.71 | TP53 (0.48) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL30344549 | 0.71 | SLC6A2 (0.43) | IRAK4OPRD1 | |
| SCHEMBL27992162 | 0.70 | IRAK4 (0.41) | IRAK4KEAP1NFE2L2OPRM1OPRD1 | |
| SCHEMBL5598341 | 0.70 | TP53 (0.44) | IRAK4KDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130953-A | Benzamide compound and preparation method thereof | JIANGXI ANLIDA CHEMICAL CO LTD | 2015-12-09 | — | — | CN | disclosed |