Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 5/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171265 | 0.82 | TP53 (0.48) | TP53DPP4DPP8DPP9DPP7 | |
| SCHEMBL5598468 | 0.82 | TP53 (0.48) | TP53DPP4DPP8DPP9DPP7 | |
| SCHEMBL5598237 | 0.82 | TP53 (0.48) | TP53DPP4DPP8DPP9DPP7 | |
| SCHEMBL6170527 | 0.80 | TP53 (0.42) | TP53DPP4DPP8DPP9DPP7 | |
| SCHEMBL5598341 | 0.77 | TP53 (0.44) | TP53DPP4DPP8DPP9DPP7 | |
| SCHEMBL5598180 | 0.74 | HTR1E (0.42) | TP53KDM4EALDH1A1HPGDIRAK4 | |
| SCHEMBL4128255 | 0.73 | IRAK4 (0.38) | TP53DPP4DPP8DPP9DPP7 | |
| SCHEMBL14862496 | 0.72 | OPRL1 (0.39) | ALDH1A1HTT | |
| SCHEMBL7368091 | 0.72 | MAPT (0.46) | DPP4DPP8DPP9DPP7KDM4E | |
| SCHEMBL30100422 | 0.71 | RPS6KB1 (0.46) | TP53DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006011035-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD. (US) | 2006-02-02 | — | — | WO | claimed |