Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983718 | 0.82 | NOS1 (0.53) | NOS1MAPTHSD17B10TDP1KDM4E | |
| SCHEMBL4477406 | 0.82 | NOS1 (0.53) | NOS1MAPTHSD17B10TDP1KDM4E | |
| SCHEMBL14738579 | 0.79 | NOS1 (0.50) | NOS1MAPTHSD17B10TDP1KDM4E | |
| SCHEMBL22430426 | 0.77 | NOS1 (0.47) | NOS1MAPTHSD17B10TDP1KDM4E | |
| Methylene Chloride SCHEMBL27730596 | 0.77 | NOS1 (0.51) | NOS1MAPTHSD17B10TDP1KDM4E | |
| SCHEMBL1855857 | 0.75 | NOS1 (1.00) | NOS1MAPTHSD17B10TDP1KDM4E | |
| SCHEMBL20078879 | 0.74 | NOS1 (0.45) | NOS1MAPTHSD17B10TDP1KDM4E | |
| SCHEMBL3064844 | 0.74 | NOS1 (0.63) | NOS1MAPTHSD17B10TDP1KDM4E | |
| SCHEMBL14231151 | 0.72 | NOS1 (0.61) | NOS1MAPTHSD17B10TDP1KDM4E | |
| SCHEMBL655480 | 0.71 | NOS1 (0.59) | NOS1MAPTHSD17B10TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096333-A | NITROSATION OF A 2-METHYLACETANILIDE | TENNECO CHEMICALS, INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-3988347-A | NITROSATION OF A 2-METHYL-ACETANILIDE WITH SODIUM NITRITE | TENNECO CHEMICALS, INC. (US) | 1976-10-26 | — | — | US | disclosed |