SCHEMBL655480

SCHEMBL655480

Nc1cccc2cn[nH]c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 3/20 0.59
MAPT P10636 4/20 0.55
KDM4E B2RXH2 3/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
TDP1 Q9NUW8 3/20 0.55
CYP3A4 P08684 3/20 0.55
HPGD P15428 3/20 0.55
HSD17B10 Q99714 3/20 0.55
CHEK1 O14757 2/20 0.55
ROCK1 Q13464 2/20 0.55
CYP1A2 P05177 2/20 0.55
CYP2C19 P33261 2/20 0.55
TSHR P16473 2/20 0.55
PLK4 O00444 1/20 0.55
AURKA O14965 1/20 0.55
DAPK3 O43293 1/20 0.55
MAP4K4 O95819 1/20 0.55
CSF1R P07333 1/20 0.55
RET P07949 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29561070 1.00 NOS1 (0.59) NOS1MAPTKDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL8102942 0.98 NOS1 (0.57) NOS1MAPTKDM4EMEN1KMT2A
SCHEMBL10596689 0.79 MAPT (0.47) NOS1MAPTKDM4EMEN1KMT2A
SCHEMBL3064844 0.77 NOS1 (0.63) NOS1MAPTKDM4EMEN1KMT2A
SCHEMBL14231151 0.76 NOS1 (0.61) NOS1MAPTKDM4EMEN1KMT2A
SCHEMBL1911926 0.74 NOS1 (0.59) NOS1MAPTKDM4EMEN1KMT2A
SCHEMBL2008172 0.74 NOS1 (0.59) NOS1MAPTKDM4EMEN1KMT2A
SCHEMBL12930782 0.74 NOS1 (0.59) NOS1MAPTKDM4EMEN1KMT2A
SCHEMBL1855857 0.74 NOS1 (1.00) NOS1MAPTKDM4EMEN1KMT2A
SCHEMBL276868 0.74 NOS1 (0.59) NOS1MAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217208-A1 CHEMICAL MECHANICAL PLANARIZATION POLISHING FOR INTERCONNECTS DIFFUSION BARRIER MATERIALS VERSUM MATERIALS US, LLC (US) 2025-10-16 WO claimed
US-11319328-B2 4β-amino substituted podophyllotoxin derivative and preparation method therefor and use thereof Tang, YaJie 2022-05-03 US claimed
CN-108285455-B 4 beta-amino substituted podophyllotoxin derivative and preparation method and application thereof 汤亚杰 2022-02-08 CN claimed
US-20200223862-A1 4Beta-Amino Substituted Podophyllotoxin Derivative and Preparation Method Therefor and Use Thereof Tang, YaJie (CN) 2020-07-16 US claimed
CN-108285455-A 4 beta-aminos replace podophyllotoxin derivative and its preparation method and application 汤亚杰 2018-07-17 CN claimed
CN-107544215-A A kind of photoresist lift off liquid 深圳新宙邦科技股份有限公司 2018-01-05 CN claimed
EP-2533053-B1 Method for the determination of the concentration of vitamin B6 in a sample BÜHLMANN LAB AG (CH) 2015-09-09 EP claimed
US-8461159-B2 Heteroaryl-substituted urea modulators of fatty acid amide hydrolase Jannsen Pharmaceutica BV (BE) 2013-06-11 US claimed
WO-2010141817-A1 HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA NV (BE) 2010-12-09 WO claimed
WO-2010068453-A1 HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA NV (BE) 2010-06-17 WO claimed
US-20060116368-A1 4-Piperidinecarboxamide modulators of vanilloid VR1 receptor JANSSEN PHARMACEUTICA N.V. (BE) 2006-06-01 US claimed
CN-1736486-A Anticancer implantation agent KONG QINGZHONG (CN) 2006-02-22 CN claimed
CN-1679952-A Anticarcinogenic medicine composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1203893-C Anti-cancer medicine composition KONG QINGZHONG (CN) 2005-06-01 CN claimed
EP-0904769-B1 Keratin fibre dye compositions containing Indazole amine derivatives and dyeing method OREAL (FR) 2002-09-25 EP claimed
CN-1326785-A Anti-cancer medicine composition KONG QINGZHONG (CN) 2001-12-19 CN claimed
US-5096785-A MIRROR AND METHOD OF MANUFACTURING SAME GLAVERBEL (BE) 1992-03-17 US claimed
US-20250304528-A1 OLIGO-BENZAMIDE ANALOGS AND THEIR USE IN CANCER TREATMENT BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-10-02 US disclosed
US-3939142-A Phenylazophenyl dyestuff HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-17 US disclosed
US-3939084-A Functional fluid compositions containing substituted pyrimidines MONSANTO COMPANY (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319328-B2 4β-amino substituted podophyllotoxin derivative and preparation method therefor and use thereof WEE1, WEE2, CYP51A1 NOS1 2060/4885MAPT 4758/4885KDM4E 21/4885
US-20250304528-A1 OLIGO-BENZAMIDE ANALOGS AND THEIR USE IN CANCER TREATMENT OGFR, OTC, HDAC6 NOS1 4182/4885MAPT 3356/4885KDM4E 836/4885
US-20200223862-A1 4Beta-Amino Substituted Podophyllotoxin Derivative and Preparation Method Therefor and Use Thereof WEE1, WEE2, CYP51A1 NOS1 2316/4885MAPT 4713/4885KDM4E 13/4885
US-20060116368-A1 4-Piperidinecarboxamide modulators of vanilloid VR1 receptor VDAC1, TRPV1, HVCN1 NOS1 4147/4885MAPT 4590/4885KDM4E 2664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.