SCHEMBL11577908

SCHEMBL11577908

[O][Si](O[SiH2]F)(c1ccccc1)c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11653537 0.77 ESR1 (0.31)
SCHEMBL3967327 0.74
SCHEMBL11577913 0.73 NR1H2 (0.32)
SCHEMBL22589000 0.69 SRC (0.31)
SCHEMBL10438592 0.69 CA4 (0.38) ALDH1A1
SCHEMBL2135654 0.68 ALDH1A1 (0.35) ALDH1A1
SCHEMBL15402646 0.64 NPSR1 (0.35) ALDH1A1
SCHEMBL3404336 0.64 ESR1 (0.31)
SCHEMBL56621 0.63 ALDH1A1 (0.36) ALDH1A1
SCHEMBL5575076 0.60 DUT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180291299-A1 ORGANOSILOXANE COMPOSITIONS DOW SILICONES CORP (US) 2018-10-11 US disclosed
US-10011801-B2 Organosiloxane compositions DOW SILICONES CORPORATION (US) 2018-07-03 US disclosed
US-20160281019-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION 2016-09-29 US disclosed
EP-3071678-A1 ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2016-09-28 EP disclosed
WO-2015077391-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2015-05-28 WO disclosed
US-4075169-A Fluorosiloxydiphenylsiloxy block copolymers GENERAL ELECTRIC COMPANY (US) 1978-02-21 US disclosed
US-4028338-A SOLVENT RESISTANT GENERAL ELECTRIC COMPANY (US) 1977-06-07 US disclosed