SCHEMBL11577938

SCHEMBL11577938

CNC(=O)Oc1ccc(S(C)(=O)=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADAMTS4 O75173 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP14 P50281 1/20 0.52
PTGS2 P35354 3/20 0.48
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
PKM P14618 1/20 0.47
ENPP2 Q13822 1/20 0.45
CYP11B1 P15538 2/20 0.43
CYP11B2 P19099 2/20 0.43
ELANE P08246 1/20 0.43
ACHE P22303 2/20 0.43
ALDH1A1 P00352 2/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12793535 0.87 PKM (0.63) ADAMTS4MMP2MMP9MMP14POLB
SCHEMBL12893245 0.84 ALDH1A1 (0.51) ADAMTS4MMP2MMP9MMP14MAPT
SCHEMBL11576441 0.82 MMP2 (0.60) ADAMTS4MMP2MMP9MMP14POLB
SCHEMBL12793824 0.81 PKM (0.63) ADAMTS4MMP2MMP9MMP14POLB
SCHEMBL1930857 0.79 MAPT (0.74) PTGS2POLBMAPTPKMENPP2
SCHEMBL6628303 0.78 ALDH1A1 (0.67) ADAMTS4PTGS2MAPTACHEALDH1A1
SCHEMBL19252080 0.77 CA12 (0.47) MMP2MMP9MMP14PTGS2POLB
SCHEMBL27825837 0.77 PTGS2 (0.50) ADAMTS4PTGS2POLBMAPTPKM
SCHEMBL7521423 0.77 PTGS2 (0.50) PTGS2POLBMAPTPKMENPP2
SCHEMBL9034912 0.76 POLB (0.53) PTGS2POLBMAPTPKMENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4126696-A 4-ALKYLSULFONYLOXYPHENYL N-ALKYLTHIOLCARBAMATES AND USE THEREOF AS FUNGICIDE FOR AGRICULTURE NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1978-11-21 US disclosed