Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196248 | 0.96 | NFE2L2 (0.47) | NFE2L2LMNASMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL27740459 | 0.94 | NFE2L2 (0.46) | NFE2L2LMNASMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL10559419 | 0.81 | LMNA (0.45) | NFE2L2LMNASMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL3839152 | 0.80 | NFE2L2 (0.42) | NFE2L2SMN1; SMN2PTGS2KDM4EALDH1A1 | |
| SCHEMBL27669602 | 0.80 | ALDH1A1 (0.45) | NFE2L2SMN1; SMN2PTGS2KDM4EALDH1A1 | |
| SCHEMBL3904409 | 0.79 | NFE2L2 (0.51) | NFE2L2LMNASMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL19275104 | 0.78 | EPAS1 (0.43) | NFE2L2LMNAPTGS2PTGS1KDM4E | |
| SCHEMBL27669603 | 0.78 | ALDH1A1 (0.44) | NFE2L2SMN1; SMN2PTGS2KDM4EALDH1A1 | |
| SCHEMBL28479379 | 0.77 | ELANE (0.61) | NFE2L2LMNASMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL7804021 | 0.76 | ELANE (0.46) | NFE2L2SMN1; SMN2KDM4EALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126696-A | 4-ALKYLSULFONYLOXYPHENYL N-ALKYLTHIOLCARBAMATES AND USE THEREOF AS FUNGICIDE FOR AGRICULTURE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1978-11-21 | — | — | US | disclosed |