Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | TOP1 | P11387 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437263 | 1.00 | TERT (0.50) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL9437261 | 1.00 | TERT (0.50) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL1157969 | 1.00 | TERT (0.50) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL9494969 | 0.95 | ALDH1A1 (0.54) | PPARGPPARDPPARAMAPTBLM | |
| SCHEMBL10392507 | 0.90 | FFAR1 (0.65) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL3495263 | 0.90 | GPR84 (0.53) | PPARDMAPTCHRM1TDP1FFAR1 | |
| SCHEMBL1157909 | 0.90 | GPR84 (0.53) | PPARDMAPTCHRM1TDP1FFAR1 | |
| SCHEMBL7609463 | 0.90 | GPR84 (0.53) | PPARDMAPTCHRM1TDP1FFAR1 | |
| SCHEMBL3495447 | 0.90 | GPR84 (0.53) | PPARDMAPTCHRM1TDP1FFAR1 | |
| SCHEMBL8574512 | 0.90 | GPR84 (0.53) | PPARDMAPTCHRM1TDP1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603932-B1 | METHODS AND COMPOSITIONS FOR THE ENZYMATIC SYNTHESIS OF GANGLIOSIDES | SENEB BIOSCIENCES INC (US) | 2012-10-03 | — | — | EP | disclosed |
| US-7888331-B2 | Ganglioside compositions and methods of use | SENEB BIOSCIENCES, INC. (US) | 2011-02-15 | — | — | US | disclosed |
| US-20070275908-A1 | Methods and Compositions for the Enzymatic Synthesis of Gangliosides | NEOSE TECHNOLOGIES, INC. (US) | 2007-11-29 | — | — | US | disclosed |
| EP-1603932-A2 | METHODS AND COMPOSITIONS FOR THE ENZYMATIC SYNTHESIS OF GANGLIOSIDES | Neose Technologies, Inc. (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080960-A2 | METHODS AND COMPOSITIONS FOR THE ENZYMATIC SYNTHESIS OF GANGLIOSIDES | NEOSE TECHNOLOGIES INC. (US) | 2004-09-23 | — | — | WO | disclosed |
| US-6407072-B1 | PROTEIN KINASE C INHIBITOR | FIDIA S.P.A. (IT) | 2002-06-18 | — | — | US | disclosed |
| US-20020072502-A1 | Novel synthetic gangliosides | NEURONYX, INC. | 2002-06-13 | — | — | US | disclosed |
| WO-2002018401-A2 | NOVEL SYNTHETIC GANGLIOSIDES | NEURONYX, INC. (US) | 2002-03-07 | — | — | WO | disclosed |
| WO-2002018402-A2 | NOVEL SYNTHETIC GANGLIOSIDES | NEURONYX, INC. (US) | 2002-03-07 | — | — | WO | disclosed |
| US-5792858-A | ACYLATING LYSOSPHINGOLIPIDS AND THEIR DERIVATIVES WITH AN ALIPHATIC ACID HAVING 2 TO 24 CARBON ATOMS, SUBSTITUTED BY ONE OR MORE POLAR GROUPS; PROTEIN-KINASE INHIBITOR, USEFUL FOR NERVOUS SYSTEM DISORDER TREATMENT | FIDIA S.P.A. (IT) | 1998-08-11 | — | — | US | disclosed |
| EP-0373038-B1 | New lysosphingolipid derivatives | FIDIA SPA (IT) | 1997-03-05 | — | — | EP | disclosed |
| US-5523294-A | THERAPY FOR NERVOUS SYSTEM DISORDERS | FIDIA S.P.A. (IT) | 1996-06-04 | — | — | US | disclosed |
| US-5519007-A | ENZYME INHIBITORS OF KINASES FOR NERVOUS SYSTEM INHIBITORS | FIDIA, S.P.A. (IT) | 1996-05-21 | — | — | US | disclosed |
| EP-0373039-B1 | New lysoganglioside derivatives | FIDIA SPA (IT) | 1994-04-06 | — | — | EP | disclosed |
| EP-0410883-A2 | Di-lysogangliosides derivatives | FIDIA S.p.A. (IT) | 1991-01-30 | — | — | EP | disclosed |
| EP-0373039-A2 | New lysoganglioside derivatives | FIDIA S.p.A. (IT) | 1990-06-13 | — | — | EP | disclosed |
| EP-0373038-A2 | New lysosphingolipid derivatives | FIDIA S.p.A. (IT) | 1990-06-13 | — | — | EP | disclosed |
| US-4501658-A | REMOVING TITANIUM MINERAL IMPURITIES | FREEPORT KAOLIN COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| US-4492628-A | FROTH FLOTATIUON, DEFLOCCULATION OF TITANIUM IMPURITIES | FREEPORT KAOLIN COMPANY (US) | 1985-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275908-A1 | Methods and Compositions for the Enzymatic Synthesis of Gangliosides | SMPD1, GBA1, SMPD2 | TERT 2686/4885PTPN1 4065/4885PPARG 2456/4885 |
| US-20020072502-A1 | Novel synthetic gangliosides | NEU2, NEU1, SGMS2 | TERT 3848/4885PTPN1 2047/4885PPARG 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.