Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PCNA | P12004 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580214 | 1.00 | MAPK1 (0.52) | MAPK1ROCK2ROCK1KMT2AMEN1 | |
| SCHEMBL11580758 | 0.81 | TAS1R3 (0.57) | MAPK1ROCK2ROCK1KMT2AMEN1 | |
| SCHEMBL11582843 | 0.81 | TAS1R3 (0.57) | MAPK1ROCK2ROCK1KMT2AMEN1 | |
| SCHEMBL10949279 | 0.79 | ALDH1A1 (0.69) | MAPK1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11582240 | 0.79 | ROCK2 (0.54) | ROCK2ROCK1ALDH1A1LMNATAS1R3 | |
| SCHEMBL11582242 | 0.79 | ROCK2 (0.54) | ROCK2ROCK1ALDH1A1LMNATAS1R3 | |
| SCHEMBL11758942 | 0.77 | PCNA (0.47) | ROCK2ROCK1PCNALMNA | |
| SCHEMBL11758950 | 0.77 | PCNA (0.47) | ROCK2ROCK1PCNALMNA | |
| SCHEMBL11581511 | 0.75 | PCNA (0.49) | KMT2AMEN1PCNAALDH1A1LMNA | |
| SCHEMBL11581516 | 0.75 | PCNA (0.49) | KMT2AMEN1PCNAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097608-A | Anti-ulcerous tyrosine derivatives | DAIICHI SEIYAKU CO., LTD. (JA) | 1978-06-27 | — | — | US | disclosed |
| US-4057629-A | ANTIULCER | DAIICHI SEIYAKU CO., LTD. (JA) | 1977-11-08 | — | — | US | disclosed |
| US-4025644-A | ANTIULCER | DAIICHI SEIYAKU CO., LTD. (JA) | 1977-05-24 | — | — | US | disclosed |