Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582240 | 1.00 | ROCK2 (0.54) | ROCK2ROCK1HPGDCTSDTAS1R3 | |
| SCHEMBL31611818 | 0.85 | TAS1R3 (0.63) | ROCK2ROCK1HPGDTAS1R3TAS1R1 | |
| SCHEMBL11581256 | 0.81 | GFER (0.57) | ROCK2ROCK1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL11581254 | 0.81 | GFER (0.57) | ROCK2ROCK1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL14819905 | 0.81 | HPGD (0.58) | ROCK2ROCK1HPGDCTSDTAS1R3 | |
| SCHEMBL11580214 | 0.79 | MAPK1 (0.52) | ROCK2ROCK1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL11580209 | 0.79 | MAPK1 (0.52) | ROCK2ROCK1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL24008823 | 0.77 | PSMB5 (0.59) | ROCK2ROCK1HPGDALDH1A1L3MBTL1 | |
| SCHEMBL7787791 | 0.77 | ROCK2 (0.51) | ROCK2ROCK1HPGDALDH1A1L3MBTL1 | |
| SCHEMBL11582843 | 0.77 | TAS1R3 (0.57) | ROCK2ROCK1TAS1R3TAS1R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097608-A | Anti-ulcerous tyrosine derivatives | DAIICHI SEIYAKU CO., LTD. (JA) | 1978-06-27 | — | — | US | claimed |
| US-4097608-A | Anti-ulcerous tyrosine derivatives | DAIICHI SEIYAKU CO., LTD. (JA) | 1978-06-27 | — | — | US | disclosed |
| US-4057629-A | ANTIULCER | DAIICHI SEIYAKU CO., LTD. (JA) | 1977-11-08 | — | — | US | disclosed |
| US-4025644-A | ANTIULCER | DAIICHI SEIYAKU CO., LTD. (JA) | 1977-05-24 | — | — | US | disclosed |