Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25660621 | 0.91 | LMNA (0.38) | LMNAALKBH5SUCNR1EGLN1HTT | |
| SCHEMBL22288206 | 0.77 | LMNA (0.43) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL9183918 | 0.77 | KDM4E (0.41) | LMNAHTTTSHRPMP22 | |
| SCHEMBL4558668 | 0.74 | TSHR (0.50) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL23495089 | 0.72 | LMNA (0.44) | LMNAALKBH5SUCNR1EGLN1SLC22A6 | |
| SCHEMBL672141 | 0.72 | KDM5A (0.47) | LMNAALKBH5SUCNR1EGLN1SLC22A6 | |
| SCHEMBL301024 | 0.72 | — | — | |
| SCHEMBL8920891 | 0.72 | KDM5A (0.47) | LMNAALKBH5SUCNR1EGLN1SLC22A6 | |
| SCHEMBL9550372 | 0.71 | LMNA (0.38) | LMNAALKBH5SUCNR1EGLN1HTT | |
| Bromide SCHEMBL15821114 | 0.70 | KDM5A (0.46) | LMNAALKBH5SUCNR1EGLN1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098881-A | COMPOSITIONS TO CONTROL THE CHRONIC EFFECTS OF EXPOSURE TO SUNLIGHT COMPRISING CONJUGATED DIENES | THE PROCTER & GAMBLE COMPANY (US) | 1978-07-04 | — | — | US | disclosed |