SCHEMBL4558668

SCHEMBL4558668

O=C(O)CCCCCCCCCCCCCC1CC=CC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
LMNA P02545 3/20 0.50
PMP22 Q01453 2/20 0.50
NFKB1 P19838 1/20 0.50
KDM5A P29375 4/20 0.46
PHF8 Q9UPP1 4/20 0.46
KDM2A Q9Y2K7 4/20 0.46
KDM4C Q9H3R0 3/20 0.46
KDM7A Q6ZMT4 1/20 0.46
GPR84 Q9NQS5 4/20 0.43
FFAR1 O14842 2/20 0.43
FFAR4 Q5NUL3 2/20 0.43
ALOX5 P09917 1/20 0.43
KDM4A O75164 1/20 0.42
HSD17B10 Q99714 3/20 0.42
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22288206 0.91 LMNA (0.43) TSHRLMNAPMP22NFKB1KDM5A
SCHEMBL27953679 0.87 KDM5A (0.44) TSHRLMNAPMP22NFKB1KDM5A
SCHEMBL25660621 0.82 LMNA (0.38) TSHRLMNAPMP22NFKB1KDM5A
SCHEMBL4449247 0.80 KDM5A (0.65) TSHRLMNAPMP22NFKB1KDM5A
SCHEMBL11848931 0.80 KDM5A (0.65) TSHRLMNAPMP22NFKB1KDM5A
SCHEMBL826408 0.80 KDM5A (0.65) TSHRLMNAPMP22NFKB1KDM5A
SCHEMBL1456488 0.80 KDM5A (0.65) TSHRLMNAPMP22NFKB1KDM5A
SCHEMBL4978263 0.80 KDM5A (0.65) TSHRLMNAPMP22NFKB1KDM5A
SCHEMBL11851432 0.80 KDM5A (0.65) TSHRLMNAPMP22NFKB1KDM5A
SCHEMBL16046794 0.80 KDM5A (0.65) TSHRLMNAPMP22NFKB1KDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090209485-A1 MODULATING ANGIOGENESIS WITH NOD FACTORS SUCH AS GLUCOSAMINE OLIGOSACCHARIDES PARISH CHRISTOPHER RICHARD 2009-08-20 US disclosed
EP-1871392-A1 MODULATING ANGIOGENESIS WITH NOD FACTORS SUCH AS GLUCOSAMINE OLIGOSACCHARIDES Parish, Christopher Richard (AU) 2008-01-02 EP disclosed
WO-2006102717-A1 MODULATING ANGIOGENESIS WITH NOD FACTORS SUCH AS GLUCOSAMINE OLIGOSACCHARIDES PARISH CHRISTOPHER RICHARD (AU) 2006-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209485-A1 MODULATING ANGIOGENESIS WITH NOD FACTORS SUCH AS GLUCOSAMINE OLIGOSACCHARIDES FLT4, UGGT1, FLT1 TSHR 4056/4885LMNA 4663/4885PMP22 3223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.