Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692615 | 0.89 | DRD2 (0.54) | DRD2HTR2AHTR2BPKMPOLB | |
| SCHEMBL11096071 | 0.89 | GAA (0.37) | DRD2HTR2AHTR2BPOLBPLG | |
| SCHEMBL11665157 | 0.88 | DRD2 (0.40) | DRD2HTR2AHTR2BPKMPOLB | |
| Hydrochloric Acid SCHEMBL11258555 | 0.87 | PKM (0.55) | DRD2HTR2AHTR2BPKMPOLB | |
| SCHEMBL9081663 | 0.84 | ALDH1A1 (0.43) | DRD2HTR2AHTR2BPOLBALDH1A1 | |
| SCHEMBL11253091 | 0.82 | ALDH1A1 (0.40) | DRD2HTR2AHTR2BPKMPOLB | |
| SCHEMBL11093150 | 0.82 | CYP1A2 (0.43) | F2F10PLAUPLATKMT2A | |
| SCHEMBL11582985 | 0.82 | HTT (0.40) | ALDH1A1HDAC1KMT2AMEN1 | |
| SCHEMBL11579586 | 0.82 | DRD2 (0.44) | DRD2HTR2AHTR2BPKMPOLB | |
| SCHEMBL4099006 | 0.82 | GAA (0.51) | DRD2HTR2AHTR2BPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |