Benzene

Benzene

SCHEMBL11580764

Cc1ccccc1NC(=O)NC(C)C.c1ccccc1

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.61
ITGB3 P05106 2/20 0.58
ITGAV P06756 2/20 0.58
ITGB1 P05556 1/20 0.58
ITGA5 P08648 1/20 0.58
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
POLB P06746 2/20 0.57
HPGD P15428 4/20 0.56
ALDH1A1 P00352 2/20 0.56
DDX3X O00571 1/20 0.56
PGR P06401 1/20 0.53
SCN1A P35498 1/20 0.53
SCN2A Q99250 1/20 0.53
SCN3A Q9NY46 1/20 0.53
MAPT P10636 3/20 0.51
GAA P10253 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
LMNA P02545 2/20 0.51
TP53 P04637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11856297 0.98 ANPEP (0.63) ANPEPITGB3ITGAVITGB1ITGA5
SCHEMBL20335118 0.86 LMNA (0.69) ANPEPITGB3ITGAVITGB1ITGA5
SCHEMBL20335119 0.86 LMNA (0.69) ANPEPITGB3ITGAVITGB1ITGA5
Toluene SCHEMBL11582399 0.84 NPC1 (0.51) ANPEPNPC1RAB9APOLBALDH1A1
SCHEMBL10748636 0.84 GAA (0.55) ANPEPNPC1RAB9APOLBALDH1A1
SCHEMBL6504061 0.83 KDM4E (0.52) ANPEPITGB3ITGAVITGB1ITGA5
SCHEMBL20335014 0.83 POLB (0.69) ANPEPITGB3ITGAVITGB1ITGA5
SCHEMBL20335016 0.83 POLB (0.69) ANPEPITGB3ITGAVITGB1ITGA5
SCHEMBL1275926 0.82 RAB9A (0.75) ITGB3ITGAVITGB1ITGA5NPC1
Benzene SCHEMBL11581029 0.81 MAPK1 (0.66) NPC1RAB9APOLBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4078913-A Herbicidal 3-(2-phenylisopropyl)urea derivatives S.D.S. BIOTECH KABUSHIKI KAISHA, 1978-03-14 US disclosed