SCHEMBL20335014

SCHEMBL20335014

Cc1ccccc1NC(=O)NC(C(=O)O)C(C)C

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.69
ALDH1A1 P00352 3/20 0.69
ANPEP P15144 1/20 0.56
CSGALNACT1 Q8TDX6 1/20 0.55
FPR2 P25090 1/20 0.54
ITGB3 P05106 2/20 0.53
ITGAV P06756 2/20 0.53
ITGB1 P05556 1/20 0.53
ITGA5 P08648 1/20 0.53
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
HPGD P15428 3/20 0.51
LMNA P02545 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
GAA P10253 1/20 0.51
DDX3X O00571 1/20 0.50
PYGL P06737 1/20 0.50
CYP2C9 P11712 1/20 0.50
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20335016 1.00 POLB (0.69) POLBALDH1A1ANPEPCSGALNACT1FPR2
SCHEMBL29776939 0.85 LMNA (0.68) POLBALDH1A1NPC1RAB9AHPGD
SCHEMBL20335118 0.84 LMNA (0.69) POLBALDH1A1ANPEPITGB3ITGAV
SCHEMBL20335119 0.84 LMNA (0.69) POLBALDH1A1ANPEPITGB3ITGAV
Benzene SCHEMBL11580764 0.83 ANPEP (0.61) POLBALDH1A1ANPEPITGB3ITGAV
SCHEMBL11856297 0.82 ANPEP (0.63) POLBALDH1A1ANPEPITGB3ITGAV
SCHEMBL20335126 0.80 FPR2 (0.73) POLBALDH1A1FPR2HPGDLMNA
SCHEMBL10795899 0.80 FPR2 (0.73) POLBALDH1A1FPR2HPGDLMNA
SCHEMBL11194644 0.80 RAB9A (0.48) POLBALDH1A1CSGALNACT1ITGB3ITGAV
SCHEMBL11194641 0.80 RAB9A (0.48) POLBALDH1A1CSGALNACT1ITGB3ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
EP-4269119-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS Sanko Co., Ltd. (JP) 2023-11-01 EP disclosed
CN-114761379-A Color-developing agent and heat-sensitive recording material 三菱化学株式会社 2022-07-15 CN disclosed
EP-3342599-B1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO LTD (JP) 2021-06-16 EP disclosed
CN-108025574-B Thermal recording medium 三光株式会社 2019-04-16 CN disclosed
US-10086634-B2 Heat-sensitive recording material SANKO CO., LTD. (JP) 2018-10-02 US disclosed
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO., LTD. (JP) 2018-07-12 US disclosed
EP-3342599-A1 HEAT-SENSITIVE RECORDING MATERIAL Sanko Co., Ltd. (JP) 2018-07-04 EP disclosed
CN-108025574-A Thermal recording medium 三光株式会社 2018-05-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL ASIC1, SCN1A, NPR1 POLB 3691/4885ALDH1A1 1820/4885ANPEP 478/4885
US-10086634-B2 Heat-sensitive recording material ASIC1, SCN1A, NPR1 POLB 3884/4885ALDH1A1 1666/4885ANPEP 540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.