Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053827 | 0.87 | MAPK1 (0.54) | MAPK1MEN1KMT2APOLBLMNA | |
| SCHEMBL11581851 | 0.86 | KCNMA1 (0.51) | MAPK1MEN1KMT2AMAPTLMNA | |
| SCHEMBL11581484 | 0.86 | PDK1 (0.39) | MAPK1MEN1KMT2AMAPTLMNA | |
| SCHEMBL11580574 | 0.85 | TBXA2R (0.39) | MAPK1MEN1KMT2APOLBMAPT | |
| SCHEMBL11580629 | 0.85 | MAPK1 (0.39) | MAPK1MEN1KMT2APOLBLMNA | |
| SCHEMBL11579368 | 0.83 | MAPT (0.45) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL11581050 | 0.83 | ALDH1A1 (0.43) | MAPK1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11052870 | 0.82 | PDK1 (0.51) | MAPK1MEN1KMT2APOLBLMNA | |
| SCHEMBL11581713 | 0.82 | MEN1 (0.45) | MAPK1MEN1KMT2APOLBMAPT | |
| SCHEMBL11049616 | 0.82 | HTT (0.50) | MAPK1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |