Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054793 | 0.87 | NPC1 (0.44) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL11581484 | 0.86 | PDK1 (0.39) | TBXA2RALDH1A1MAPTKCNMA1MEN1 | |
| SCHEMBL11581851 | 0.86 | KCNMA1 (0.51) | TBXA2RALDH1A1MAPTKCNMA1MEN1 | |
| SCHEMBL11580943 | 0.85 | MAPK1 (0.45) | TBXA2RALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL11580629 | 0.85 | MAPK1 (0.39) | TBXA2RALDH1A1POLBKCNMA1MEN1 | |
| SCHEMBL11581050 | 0.83 | ALDH1A1 (0.43) | TBXA2RALDH1A1KCNMA1MEN1KMT2A | |
| SCHEMBL11579368 | 0.83 | MAPT (0.45) | TBXA2RALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11577888 | 0.82 | MEN1 (0.38) | ALDH1A1MAPTPOLBKCNMA1MEN1 | |
| SCHEMBL11052138 | 0.82 | KMT2A (0.40) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11578638 | 0.82 | KMT2A (0.40) | TBXA2RALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |