Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DBH | P09172 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TPO | P07202 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | LPO | P22079 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656963 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTMMP2MPOOPRM1 | |
| SCHEMBL5792155 | 0.80 | MMP2 (0.34) | ALDH1A1POLBMAPTMMP2MPO | |
| SCHEMBL7752446 | 0.79 | ALDH1A1 (0.34) | ALDH1A1POLBMAPTMMP2MPO | |
| SCHEMBL338056 | 0.79 | TYMP (0.32) | TYMP | |
| SCHEMBL11583565 | 0.79 | TYMP (0.37) | ALDH1A1POLBMAPTHPGDTDP1 | |
| SCHEMBL27672161 | 0.77 | KDM1A (0.39) | ALDH1A1OPRM1HPGDTDP1MEN1 | |
| SCHEMBL41241 | 0.77 | KDM1A (0.39) | ALDH1A1OPRM1HPGDTDP1MEN1 | |
| SCHEMBL4278697 | 0.76 | MPO (0.34) | ALDH1A1POLBMAPTMMP2MPO | |
| SCHEMBL26948699 | 0.76 | ALDH1A1 (0.49) | ALDH1A1POLBMAPTCYP3A4HPGD | |
| SCHEMBL29161647 | 0.76 | OPRM1 (0.34) | ALDH1A1POLBMAPTMMP2MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088751-A | SHAVING CREAM, SHAMPOO, LOTION, 2-THIO-4-OXYPYRIMIDINE OR THIOHYDANTOIN AND HYDROGEN PEROXIDE, EXOTHERMIC REDOX REACTION | COLGATE-PALMOLIVE COMPANY (US) | 1978-05-09 | — | — | US | disclosed |