Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 9/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580932 | 0.82 | GAA (0.62) | GAAALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL548073 | 0.80 | TGM2 (0.51) | GAATGM2PSMB5ALDH1A1TSHR | |
| SCHEMBL4340637 | 0.77 | GAA (0.56) | GAATGM2PSMB5ALDH1A1TSHR | |
| SCHEMBL9321482 | 0.75 | TGM2 (0.57) | TGM2ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL11582575 | 0.75 | GAA (0.48) | GAAALDH1A1TDP1KMT2ACYP1A2 | |
| SCHEMBL5534309 | 0.73 | MET (0.43) | ALDH1A1TSHRHMGB1CXCL12THRB | |
| SCHEMBL8377055 | 0.73 | CA1 (0.48) | GAAALDH1A1TSHRHMGB1CXCL12 | |
| SCHEMBL11580530 | 0.72 | GAA (0.48) | GAATGM2ALDH1A1TSHRMAPK1 | |
| SCHEMBL27801542 | 0.72 | TGM2 (0.58) | GAATGM2THRATHRBEGFR | |
| SCHEMBL844941 | 0.71 | TSHR (0.59) | GAATGM2ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4131644-A | TREATING POLYBUTADIENE WITH A LEWIS ACID AND A SULFUR MELT, CARBONIZING | UBE INDUSTRIES, INC. (JP) | 1978-12-26 | — | — | US | disclosed |