Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582903 | 0.89 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDHSD17B10S1PR3 | |
| SCHEMBL11584035 | 0.88 | LMNA (0.47) | KDM4EALDH1A1HPGDHSD17B10S1PR3 | |
| SCHEMBL11585100 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10S1PR3 | |
| SCHEMBL11583246 | 0.83 | MAPT (0.54) | KDM4EALDH1A1HPGDHSD17B10S1PR3 | |
| SCHEMBL11584031 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10S1PR3 | |
| SCHEMBL11582677 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDHSD17B10S1PR3 | |
| SCHEMBL11584181 | 0.80 | S1PR3 (0.46) | KDM4EALDH1A1HPGDHSD17B10S1PR3 | |
| SCHEMBL11583826 | 0.80 | MAPT (0.47) | KDM4EALDH1A1HPGDHSD17B10S1PR3 | |
| SCHEMBL11586538 | 0.80 | MAPT (0.49) | KDM4EALDH1A1HPGDHSD17B10S1PR3 | |
| SCHEMBL29290485 | 0.79 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDHSD17B10S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134975-A | PYRIDO(1,2,-D)(1,4,6)BENZOXADIAZOCINES OR PYRIDO(1,2,-C)(1,3,5)BENZOXADIAZEPINES | E. R. SQUIBB & SONS, INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4101551-A | WATER INSOLUBILITY, AFFINITY FOR POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |
| US-3957806-A | STIMULANTS, MUSCLE RELAXANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-05-18 | — | — | US | disclosed |