Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | DVL1 | O14640 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583037 | 0.86 | KDM4E (0.48) | POLBGFERMAPK1CYP1A2CYP2C9 | |
| SCHEMBL1286026 | 0.86 | MEN1 (0.47) | POLBCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL1285933 | 0.81 | MEN1 (0.49) | POLBMAPK1PPARGLMNAMEN1 | |
| SCHEMBL11699547 | 0.81 | FABP4 (0.45) | POLBMEN1ALDH1A1KMT2AFABP4 | |
| SCHEMBL11702312 | 0.81 | MAPK1 (0.41) | POLBGFERMAPK1PPARGCYP1A2 | |
| SCHEMBL4583233 | 0.77 | CYP1A2 (0.45) | MAPK1CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL11584038 | 0.77 | GPR17 (0.46) | POLBGFERMAPK1PPARGCYP2C9 | |
| SCHEMBL11583248 | 0.76 | MAPK1 (0.48) | POLBGFERMAPK1PPARGCYP1A2 | |
| SCHEMBL8962250 | 0.76 | POLB (0.48) | POLBMEN1ALDH1A1KMT2AFABP4 | |
| SCHEMBL7633011 | 0.76 | CA1 (0.44) | ALDH1A1FABP4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101551-A | WATER INSOLUBILITY, AFFINITY FOR POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |
| US-4024144-A | SULFONIC ACID GROUPS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |