Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19040679 | 0.85 | AKR1C3 (0.46) | POLBFEN1ALDH1A1KMT2AMEN1 | |
| SCHEMBL29676384 | 0.84 | NPSR1 (0.47) | POLBALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL34677 | 0.84 | NPSR1 (0.47) | POLBALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1482049 | 0.82 | POLB (0.48) | POLBALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29435078 | 0.81 | ALOX15 (0.48) | POLBALDH1A1MAPTSMN1; SMN2ALOX15 | |
| SCHEMBL347237 | 0.81 | ALOX15 (0.48) | POLBALDH1A1MAPTSMN1; SMN2ALOX15 | |
| SCHEMBL11610684 | 0.78 | MMP2 (0.55) | SMN1; SMN2ALOX15 | |
| SCHEMBL11608183 | 0.77 | SLC16A1 (0.44) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11607950 | 0.77 | ALOX15 (0.44) | ALOX15 | |
| SCHEMBL11583249 | 0.76 | POLB (0.44) | POLBALDH1A1KMT2AMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |