Sequoiaflavone

Sequoiaflavone

SCHEMBL1158361

COc1cc(O)c2c(=O)cc(-c3ccc(O)c(-c4c(O)cc(O)c5c(=O)cc(-c6ccc(O)cc6)oc45)c3)oc2c1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.73
▸ KMT2A Q03164 3/20 0.73
▸ MAPT P10636 3/20 0.73
▸ USP2 O75604 2/20 0.73
▸ TP53 P04637 2/20 0.73
▸ KDM4E B2RXH2 1/20 0.73
▸ HPGD P15428 1/20 0.73
▸ ALOX15 P16050 1/20 0.73
▸ HBB P68871 1/20 0.73
▸ HSD17B10 Q99714 1/20 0.73
▸ FLT3 P36888 2/20 0.71
▸ IP6K2 Q9UHH9 2/20 0.71
▸ MKNK2 Q9HBH9 1/20 0.71
▸ APP P05067 6/20 0.69
▸ TDP1 Q9NUW8 2/20 0.66
▸ THRB P10828 1/20 0.66
▸ PLG P00747 1/20 0.65
▸ MAOB P27338 2/20 0.65
▸ CYP19A1 P11511 1/20 0.65
▸ PARP1 P09874 3/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sequoiaflavone SCHEMBL30646160 1.00 MEN1 (0.73) MEN1KMT2AMAPTUSP2TP53
Podocarpusflavone B SCHEMBL29496271 0.96 MAPT (0.73) MEN1KMT2AMAPTUSP2TP53
Podocarpusflavone B SCHEMBL27350627 0.96 MAPT (0.73) MEN1KMT2AMAPTUSP2TP53
Podocarpusflavone A SCHEMBL29496316 0.92 MEN1 (0.72) MEN1KMT2AMAPTUSP2TP53
Podocarpusflavone A SCHEMBL25937932 0.92 MEN1 (0.72) MEN1KMT2AMAPTUSP2TP53
Ginkgetin SCHEMBL30612275 0.92 MAPT (0.86) MEN1KMT2AMAPTUSP2TP53
Ginkgetin SCHEMBL31303838 0.92 MAPT (0.86) MEN1KMT2AMAPTUSP2TP53
Ginkgetin SCHEMBL888410 0.92 MAPT (0.86) MEN1KMT2AMAPTUSP2TP53
Amentoflavone SCHEMBL312563 0.89 MEN1 (0.80) MEN1KMT2AMAPTUSP2TP53
Amentoflavone SCHEMBL29497539 0.89 MEN1 (0.80) MEN1KMT2AMAPTUSP2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2329831-A2 Stimulation of hair growth by Ginko biloba flavanoids Osteoscreen, Inc. (US) 2011-06-08 — — EP claimed
EP-0126691-B1 PROCESS FOR PREPARING A THERAPEUTICALLY USEFUL EXTRACT FROM BRACKENRIDGEA ZANGUEBARICA, EXTRACT AND SUCH A MEDICINE INVERNI DELLA BEFFA S.P.A. (IT) 1988-04-20 — — EP claimed
EP-0126691-A1 Process for preparing a therapeutically useful extract from Brackenridgea zanguebarica, extract and such a medicine INVERNI DELLA BEFFA S.P.A. (IT) 1984-11-28 — — EP claimed
US-20250228814-A1 COMBINATION THERAPIES FOR THE TREATMENT OF VIRAL INFECTIONS FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2025-07-17 — — US disclosed
WO-2023250111-A1 COMBINATION THERAPIES FOR THE TREATMENT OF VIRAL INFECTIONS FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2023-12-28 — — WO disclosed
US-20230233514-A1 ANTIVIRAL COMPOUNDS AND METHODS OF USING THE SAME FLAGSHIP PIONEERING, INC. 2023-07-27 — — US disclosed
US-20230233514-A1 ANTIVIRAL COMPOUNDS AND METHODS OF USING THE SAME FLAGSHIP PIONEERING, INC. 2023-07-27 — — US disclosed
CN-103141521-B Cephalotaxus sinensis Li. insecticide and its preparation method RES & DEV CT OF BIORATIONAL PESTICIDE YANGLING NONGKEDA 2015-02-18 — — CN disclosed
CN-103141521-A Cephalotaxus sinensis Li. insecticide and its preparation method RES & DEV CT OF BIORATIONAL PESTICIDE YANGLING NONGKEDA 2013-06-12 — — CN disclosed
US-8367121-B2 Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease FLORIDA A & M UNIVERSITY (US) 2013-02-05 — — US disclosed
EP-1684774-B1 STIMULATION OF HAIR GROWTH BY ISOGINKGETIN OSTEOSCREEN INC (US) 2012-08-29 — — EP disclosed
WO-2003061572-A9 ANTI-INFLAMMATORY FORMULATIONS HAINES DAVID (US) 2004-02-26 — — WO disclosed
US-20030170328-A1 Anti-inflammatory formulations NATURAL ALTERNATIVES INTERNATIONAL, INC. 2003-09-11 — — US disclosed
WO-2003061572-A2 ANTI-INFLAMMATORY FORMULATIONS HAINES DAVID (US) 2003-07-31 — — WO disclosed
EP-1299119-A2 IMMUNOSUPPRESSIVE COMPOSITIONS COMPRISING AN IMMUNOPHILIN-BINDING COMPOUND AND A GINKGOLIDE COMPOUND Haines, David (US) 2003-04-09 — — EP disclosed
US-6328999-B1 Ginkgo biloba leaf extracts with a reduced 4′-O-methylpyridoxine and biflavone content DR. WILLMAR SCHWABE GMBH & CO. (DE) 2001-12-11 — — US disclosed
WO-2001085206-A2 IMMUNOSUPPRESSIVE COMPOSITIONS COMPRISING AN IMMUNOPHILIN-BINDING COMPOUND AND A GINGKOLIDE COMPOUND HAINES DAVID (US) 2001-11-15 — — WO disclosed
EP-0126691-B1 PROCESS FOR PREPARING A THERAPEUTICALLY USEFUL EXTRACT FROM BRACKENRIDGEA ZANGUEBARICA, EXTRACT AND SUCH A MEDICINE INVERNI DELLA BEFFA S.P.A. (IT) 1988-04-20 — — EP disclosed
EP-0126691-A1 Process for preparing a therapeutically useful extract from Brackenridgea zanguebarica, extract and such a medicine INVERNI DELLA BEFFA S.P.A. (IT) 1984-11-28 — — EP disclosed
EP-0126691-A1 Process for preparing a therapeutically useful extract from Brackenridgea zanguebarica, extract and such a medicine INVERNI DELLA BEFFA S.P.A. (IT) 1984-11-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233514-A1 ANTIVIRAL COMPOUNDS AND METHODS OF USING THE SAME ACE2, ACE, EIF2AK2 MEN1 4255/4885KMT2A 2967/4885MAPT 3743/4885
US-20250228814-A1 COMBINATION THERAPIES FOR THE TREATMENT OF VIRAL INFECTIONS HAVCR2, EIF2AK2, MAVS MEN1 3073/4885KMT2A 3798/4885MAPT 1798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback