Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | USP2 | O75604 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | HBB | P68871 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | MAOB | P27338 | 2/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.71 |
| ▸ | APP | P05067 | 5/20 | 0.69 |
| ▸ | FLT3 | P36888 | 2/20 | 0.65 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Podocarpusflavone B SCHEMBL27350627 | 1.00 | MAPT (0.73) | MAPTMEN1KMT2AUSP2TP53 | |
| Podocarpusflavone A SCHEMBL25937932 | 0.96 | MEN1 (0.72) | MAPTMEN1KMT2AUSP2TP53 | |
| Podocarpusflavone A SCHEMBL29496316 | 0.96 | MEN1 (0.72) | MAPTMEN1KMT2AUSP2TP53 | |
| Sequoiaflavone SCHEMBL1158361 | 0.96 | MEN1 (0.73) | MAPTMEN1KMT2AUSP2TP53 | |
| Sequoiaflavone SCHEMBL30646160 | 0.96 | MEN1 (0.73) | MAPTMEN1KMT2AUSP2TP53 | |
| Heveaflavone SCHEMBL30646163 | 0.92 | APP (0.72) | MAPTMEN1KMT2AUSP2TP53 | |
| Sciadopitisin SCHEMBL30996894 | 0.92 | MAPT (0.86) | MAPTMEN1KMT2AUSP2TP53 | |
| Heveaflavone SCHEMBL27350698 | 0.92 | APP (0.72) | MAPTMEN1KMT2AUSP2TP53 | |
| Sciadopitisin SCHEMBL1158050 | 0.92 | MAPT (0.86) | MAPTMEN1KMT2AUSP2TP53 | |
| 7'',4'''-Dimethylamentoflavone SCHEMBL30646161 | 0.88 | APP (0.72) | MAPTMEN1KMT2AUSP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498297-B1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM | STALICLA S A (CH) | 2023-06-21 | — | — | EP | disclosed |
| US-11439627-B2 | Pharmaceutical composition for the treatment of autism | Stalicla S.A. (CH) | 2022-09-13 | — | — | US | disclosed |
| EP-3984555-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM | Stalicla S.A. (CH) | 2022-04-20 | — | — | EP | disclosed |