SCHEMBL11584032

SCHEMBL11584032

O=C(O)c1ccc(S(=O)(=O)Nc2cccc(Cl)c2)cc1C(=O)O

nearest known ligand 0.81

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.81
TSHR P16473 2/20 0.81
MEN1 O00255 7/20 0.64
KMT2A Q03164 7/20 0.64
GPR27 Q9NS67 2/20 0.60
PGR P06401 3/20 0.60
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
PKM P14618 1/20 0.56
CYP2C19 P33261 1/20 0.56
ACLY P53396 1/20 0.55
CYP19A1 P11511 1/20 0.55
HTT P42858 1/20 0.55
ALOX15 P16050 1/20 0.52
AVPR2 P30518 1/20 0.52
LIMK2 P53671 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11584745 0.85 KMT2A (0.60) ALDH1A1TSHRMEN1KMT2APKM
SCHEMBL11583053 0.83 MEN1 (0.59) ALDH1A1TSHRMEN1KMT2AGPR27
SCHEMBL664321 0.83 KMT2A (0.75) ALDH1A1TSHRMEN1KMT2AGPR27
SCHEMBL8251165 0.82 PFKFB3 (0.67) ALDH1A1TSHRMEN1KMT2APGR
SCHEMBL9997096 0.81 ALDH1A1 (0.69) ALDH1A1TSHRPGRPKMACLY
SCHEMBL11585563 0.80 CASP3 (0.64) ALDH1A1TSHRMEN1KMT2APGR
SCHEMBL11585081 0.80 MCL1 (0.60) ALDH1A1TSHRMEN1KMT2AGPR27
SCHEMBL29369447 0.79 PFKFB3 (0.71) ALDH1A1TSHRMEN1KMT2APGR
SCHEMBL2831061 0.79 PFKFB3 (0.71) ALDH1A1TSHRMEN1KMT2APGR
SCHEMBL29875309 0.79 PFKFB3 (0.71) ALDH1A1TSHRMEN1KMT2APGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4101551-A WATER INSOLUBILITY, AFFINITY FOR POLYESTERS BAYER AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed