Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11586950 | 1.00 | TSHR (0.43) | TSHRALDH1A1HTTCES1CES2 | |
| SCHEMBL245184 | 0.99 | TSHR (0.44) | TSHRALDH1A1HTTCES1CES2 | |
| SCHEMBL11586797 | 0.95 | TSHR (0.46) | TSHRALDH1A1HTTCES1CES2 | |
| SCHEMBL11588492 | 0.90 | ALDH1A1 (0.44) | TSHRALDH1A1HTTCES1LMNA | |
| Ether SCHEMBL9750209 | 0.84 | ALDH1A1 (0.46) | TSHRALDH1A1HTTCES1LMNA | |
| Methoxymethane SCHEMBL9749754 | 0.83 | TSHR (0.50) | TSHRALDH1A1HTTCES1LMNA | |
| SCHEMBL197860 | 0.83 | ALDH1A1 (0.56) | TSHRALDH1A1HTTCES1LMNA | |
| SCHEMBL11307176 | 0.81 | PLA2G4B (0.43) | TSHRALDH1A1CES1CES2LMNA | |
| SCHEMBL11314618 | 0.81 | PLA2G4B (0.43) | TSHRALDH1A1CES1CES2LMNA | |
| SCHEMBL11320202 | 0.81 | PLA2G4B (0.43) | TSHRALDH1A1CES1CES2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4081492-A | POLYEPOXIDE BINDERS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-28 | — | — | US | disclosed |
| US-4014771-A | POLYEPOXIDES, BINDERS FOR PRINTING INKS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |