SCHEMBL11107779

SCHEMBL11107779

CS(=O)(=O)c1nc(Cl)cc(Br)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GLP1R P43220 5/20 0.33
BPTF Q12830 1/20 0.33
AURKA O14965 1/20 0.32
AURKB Q96GD4 1/20 0.32
NPSR1 Q6W5P4 3/20 0.32
TLR9 Q9NR96 3/20 0.32
SDHB P21912 2/20 0.32
STAT3 P40763 2/20 0.32
STAT1 P42224 2/20 0.32
RAB9A P51151 2/20 0.32
KMT2A Q03164 2/20 0.32
TP53 P04637 2/20 0.32
S1PR1 P21453 2/20 0.32
MAPK1 P28482 2/20 0.32
HTT P42858 2/20 0.32
HSD17B10 Q99714 2/20 0.32
MEN1 O00255 1/20 0.32
S1PR4 O95977 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8667201 0.85 LMNA (0.56) LMNASMN1; SMN2BPTFNPSR1TLR9
SCHEMBL63292 0.85 LMNA (0.50) LMNASMN1; SMN2GLP1RBPTFAURKA
SCHEMBL8666206 0.78 SMN1; SMN2 (0.78) LMNASMN1; SMN2GLP1RNPSR1TLR9
SCHEMBL6296316 0.78 LMNA (0.44) LMNASMN1; SMN2GLP1RAURKAAURKB
SCHEMBL11585339 0.78 LMNA (0.44) LMNASMN1; SMN2GLP1RBPTFAURKA
SCHEMBL13703901 0.76 LMNA (0.42) LMNASMN1; SMN2GLP1RBPTFAURKA
SCHEMBL8597269 0.76 LMNA (0.42) LMNASMN1; SMN2GLP1RBPTFAURKA
SCHEMBL2614925 0.73 BPTF (0.55) LMNASMN1; SMN2BPTFAURKAAURKB
SCHEMBL20578730 0.73 SDHB (0.42) LMNASMN1; SMN2GLP1RAURKAAURKB
SCHEMBL29010137 0.73 POLB (0.41) LMNASMN1; SMN2GLP1RAURKAAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0108924-A1 Heavy metal-containing formazane dyestuffs, methods for their preparation and their use in the dyeing and printing of fibre materials BAYER AG (DE) 1984-05-23 EP disclosed