Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GLP1R | P43220 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | SDHB | P21912 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63292 | 0.85 | LMNA (0.50) | LMNASMN1; SMN2GLP1RBPTFAURKA | |
| SCHEMBL27323912 | 0.80 | ALDH1A1 (0.33) | LMNASMN1; SMN2GLP1RNOS3NOS1 | |
| SCHEMBL10519534 | 0.78 | NOS3 (0.50) | LMNASMN1; SMN2GLP1RNOS3NOS1 | |
| SCHEMBL6296316 | 0.78 | LMNA (0.44) | LMNASMN1; SMN2GLP1RAURKAAURKB | |
| SCHEMBL11585339 | 0.78 | LMNA (0.44) | LMNASMN1; SMN2GLP1RBPTFAURKA | |
| SCHEMBL13703901 | 0.76 | LMNA (0.42) | LMNASMN1; SMN2GLP1RBPTFAURKA | |
| SCHEMBL11107779 | 0.76 | LMNA (0.47) | LMNASMN1; SMN2GLP1RBPTFAURKA | |
| SCHEMBL9322839 | 0.74 | CYP2D6 (0.42) | LMNASMN1; SMN2GLP1RKDM4EALDH1A1 | |
| SCHEMBL8666206 | 0.74 | SMN1; SMN2 (0.78) | LMNASMN1; SMN2GLP1RKDM4EALDH1A1 | |
| SCHEMBL11512311 | 0.74 | LMNA (0.48) | LMNASMN1; SMN2GLP1RALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5772990-A | Composition for slowing down the loss of hair based on pyrimidine N-oxides triaminosubstituted or their sulfoconjugated | L'OREAL (FR) | 1998-06-30 | — | — | US | disclosed |
| EP-0519819-B1 | Composition for use to reduce hair loss and to induce and stimulate its growth, containing derivatives of 2,4,6-triaminopyrimidin-N-oxide and the new derivatives of 2,4,6-triaminopyrimidin-N-oxide | OREAL (FR) | 1995-07-19 | — | — | EP | disclosed |
| EP-0519819-A1 | Composition for use to reduce hair loss and to induce and stimulate its growth, containing derivatives of 2,4,6-triaminopyrimidin-N-oxide and the new derivatives of 2,4,6-triaminopyrimidin-N-oxide | L'OREAL (FR) | 1992-12-23 | — | — | EP | disclosed |
| US-4199583-A | 4-AMINO-6-HALO-2-METHYLTHIO-, METHOXY-, METHYLSULFINYL- OR METHYLSULFONYL-PYRIMIDINES | THE UPJOHN COMPANY (US) | 1980-04-22 | — | — | US | disclosed |