Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399310 | 0.86 | CA12 (0.41) | TDP1L3MBTL1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL11592055 | 0.81 | TDP1 (0.46) | TDP1L3MBTL1NPC1SMN1; SMN2HAO1 | |
| SCHEMBL16508363 | 0.81 | TDP1 (0.46) | TDP1L3MBTL1NPC1SMN1; SMN2HAO1 | |
| SCHEMBL28636936 | 0.79 | TP53 (0.48) | TDP1NPC1KMT2AMAPTHPGD | |
| SCHEMBL11424324 | 0.79 | MCL1 (0.49) | TDP1NPC1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL25671816 | 0.78 | TDP1 (0.39) | TDP1L3MBTL1NPC1SMN1; SMN2HAO1 | |
| SCHEMBL25141394 | 0.76 | TDP1 (0.38) | TDP1L3MBTL1NPC1SMN1; SMN2HAO1 | |
| SCHEMBL1159876 | 0.76 | ALDH1A1 (0.35) | TDP1SMN1; SMN2LMNAALDH1A1ATM | |
| SCHEMBL18738950 | 0.76 | KDM4E (0.46) | TDP1L3MBTL1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL47874 | 0.76 | KMT2A (0.57) | TDP1L3MBTL1NPC1SMN1; SMN2HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067903-A | Manufacture of arylamines | BASF AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |