Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11592055 | 0.86 | TDP1 (0.46) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL11586044 | 0.81 | TDP1 (0.44) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL10880074 | 0.74 | MEN1 (0.33) | KMT2AMEN1 | |
| SCHEMBL25671816 | 0.74 | TDP1 (0.39) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL2288471 | 0.73 | TDP1 (0.50) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL2383687 | 0.73 | ACHE (0.48) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL4859496 | 0.73 | TDP1 (0.46) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL25141394 | 0.72 | TDP1 (0.38) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL47874 | 0.72 | KMT2A (0.57) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL8443586 | 0.71 | ACHE (0.46) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294118-A1 | WATER SOLUBLE FLUORESCENT COMPOUNDS | BIOSEARCH TECHNOLOGIES, INC. (US) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294118-A1 | WATER SOLUBLE FLUORESCENT COMPOUNDS | ABCG2, AQP1, AQP3 | TDP1 1861/4885SMN1; SMN2 3300/4885L3MBTL1 2376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.