Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11588457 | 0.88 | PDK2 (0.39) | IDO1ALDH1A1MAPTPKMGAA | |
| SCHEMBL11586897 | 0.88 | HPRT1 (0.43) | ALDH1A1TSHRHSD17B10MAPTPKM | |
| SCHEMBL7049360 | 0.75 | EGFR (0.35) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL7043743 | 0.72 | MEN1 (0.36) | ALDH1A1MAPTEGFRAKR1C4AKR1C3 | |
| SCHEMBL8942751 | 0.69 | GAA (0.41) | IDO1ALDH1A1TSHRCYP3A4MAPT | |
| SCHEMBL11587496 | 0.67 | MAPT (0.36) | IDO1ALDH1A1MAPTPKMGAA | |
| SCHEMBL13301890 | 0.66 | S100A4 (0.57) | ALDH1A1MAPTPKMGAAHPRT1 | |
| SCHEMBL11586454 | 0.65 | IDO1 (0.35) | IDO1ALDH1A1MAPTPKMGAA | |
| SCHEMBL14113263 | 0.64 | GABRA1 (0.32) | GABRA1GABRG2GABRB3GABRB1GABRB2 | |
| SCHEMBL21917286 | 0.64 | MAPT (0.43) | IDO1ALDH1A1MAPTPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29554-E | Organic photoconductive members comprising dicyanomethylene substituted fluorene sensitizers | ADDRESSOGRAPH-MULTIGRAPH CORPORATION (US) | 1978-02-28 | — | — | US | claimed |
| US-RE29554-E | Organic photoconductive members comprising dicyanomethylene substituted fluorene sensitizers | ADDRESSOGRAPH-MULTIGRAPH CORPORATION (US) | 1978-02-28 | — | — | US | disclosed |