Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043743 | 0.86 | MEN1 (0.36) | EGFRALDH1A1 | |
| SCHEMBL7049632 | 0.77 | EGFR (0.33) | EGFRALDH1A1 | |
| SCHEMBL7049233 | 0.76 | EGFR (0.38) | EGFRALDH1A1CYP3A4TSHRGABRA1 | |
| SCHEMBL11587176 | 0.75 | IDO1 (0.37) | EGFRALDH1A1CYP3A4TSHRRECQL | |
| SCHEMBL7047507 | 0.74 | EGFR (0.36) | EGFR | |
| SCHEMBL10049619 | 0.73 | EGFR (0.32) | EGFR | |
| SCHEMBL10049507 | 0.70 | EGFR (0.34) | EGFR | |
| SCHEMBL7051502 | 0.70 | UCHL1 (0.33) | EGFR | |
| SCHEMBL7049277 | 0.68 | S100A4 (0.40) | EGFRCYP3A4TSHRGABRA1GABRG2 | |
| SCHEMBL21851280 | 0.68 | S100A4 (0.40) | EGFRGABRA1GABRG2GABRB3GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | disclosed |