Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 5/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1821613 | 0.82 | TAAR1 (0.50) | PKMTAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL27449727 | 0.76 | TAAR1 (0.47) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27332749 | 0.76 | TAAR1 (0.52) | PKMTAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL29858834 | 0.76 | PKM (0.66) | PKMTAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL10499879 | 0.75 | MAOA (0.46) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28291460 | 0.75 | IDO1 (0.63) | PKMTAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL28565719 | 0.74 | TAAR1 (0.58) | PKMTAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL20940182 | 0.74 | TAAR1 (0.44) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6049237 | 0.73 | LMNA (0.52) | TAAR1IDO1LMNASMN1; SMN2 | |
| SCHEMBL27857019 | 0.72 | TAAR1 (0.43) | TAAR1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094895-A | Process for preparation of O-(substituted)benzyl thiocarbamates | STAUFFER CHEMICAL COMPANY (US) | 1978-06-13 | — | — | US | disclosed |
| US-4062971-A | S-alkyl carbonimidothioates and their use as aphicides | STAUFFER CHEMICAL COMPANY (US) | 1977-12-13 | — | — | US | disclosed |