Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481069 | 0.85 | HSP90AA1 (0.35) | HSP90AA1ATMTRPM8SIGMAR1LMNA | |
| SCHEMBL11383887 | 0.84 | HSP90AA1 (0.39) | HSP90AA1ATMTRPM8LMNAALDH1A1 | |
| SCHEMBL10958394 | 0.81 | RORC (0.45) | TDP1TRPM8LMNAALDH1A1GAA | |
| SCHEMBL11680303 | 0.79 | ALDH1A1 (0.39) | HSP90AA1ATMTRPM8LMNAALDH1A1 | |
| SCHEMBL14707100 | 0.77 | LMNA (0.39) | HSP90AA1ATMTRPM8SIGMAR1LMNA | |
| SCHEMBL11382815 | 0.75 | UTS2R (0.38) | ATMALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10371941 | 0.75 | THRB (0.42) | TRPM8LMNAALDH1A1GAACYP3A4 | |
| SCHEMBL11416899 | 0.75 | TP53 (0.44) | TRPM8SIGMAR1LMNAALDH1A1CYP3A4 | |
| SCHEMBL11397051 | 0.74 | POLB (0.39) | TDP1LMNAALDH1A1TP53TSHR | |
| SCHEMBL10994096 | 0.73 | ALDH1A1 (0.38) | TDP1HSP90AA1ATMTRPM8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096167-A | Fungicidal and herbicidal alpha-haloacetanilides | CHEVRON RESEARCH COMPANY (US) | 1978-06-20 | — | — | US | disclosed |