Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 10/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11591247 | 0.80 | NQO2 (0.44) | RXRAGAAHSD17B10DDB1CRBN | |
| SCHEMBL11589606 | 0.79 | ALDH1A1 (0.54) | RXRAGAAHSD17B10CYP1A2DDB1 | |
| SCHEMBL29377253 | 0.77 | KDM4E (0.56) | RXRAGAAHSD17B10MAPK1TDP1 | |
| SCHEMBL76177 | 0.77 | KDM4E (0.56) | RXRAGAAHSD17B10MAPK1TDP1 | |
| SCHEMBL5701185 | 0.73 | CDK4 (0.41) | GAAHSD17B10CYP1A2CYP3A4TSHR | |
| SCHEMBL1772049 | 0.72 | KDM4E (0.64) | GAAARHSD17B10PGRKDM4E | |
| Perchlorate SCHEMBL30042407 | 0.70 | KDM4E (0.49) | RXRAGAAHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL21957305 | 0.69 | AR (0.54) | GAAARHSD17B10ALOX15TSHR | |
| SCHEMBL17537351 | 0.69 | CYP1A2 (0.49) | GAAARHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL1773043 | 0.65 | KDM4E (0.48) | GAAARHSD17B10PGRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103257-A | BLUE TO NEAR ULTRAVIOLET | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1978-07-25 | — | — | US | claimed |