SCHEMBL29377253

SCHEMBL29377253

COc1cc(=O)n(C)c2nc(N(C)C)ccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.56
ALDH1A1 P00352 2/20 0.56
HPGD P15428 2/20 0.56
HSD17B10 Q99714 2/20 0.56
GLA P06280 1/20 0.56
GAA P10253 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
ADORA1 P30542 1/20 0.52
MAPT P10636 2/20 0.44
CYP19A1 P11511 6/20 0.43
NQO2 P16083 6/20 0.43
TDP1 Q9NUW8 2/20 0.37
BRD9 Q9H8M2 2/20 0.36
BRD7 Q9NPI1 2/20 0.36
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
RXRA P19793 1/20 0.35
THRB P10828 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76177 1.00 KDM4E (0.56) KDM4EALDH1A1HPGDHSD17B10GLA
Perchlorate SCHEMBL30042407 0.92 KDM4E (0.49) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL28428097 0.82 KDM4E (0.54) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL11591247 0.80 NQO2 (0.44) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL11589606 0.79 ALDH1A1 (0.54) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL11590400 0.77 RXRA (0.56) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL11589892 0.77 ADORA1 (0.52) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL5701185 0.73 CDK4 (0.41) ALDH1A1HPGDHSD17B10GAAADORA1
SCHEMBL3019661 0.71 ADORA2A (0.49) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL11379787 0.65 KCNA3 (0.61) KDM4EALDH1A1HPGDHSD17B10GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4652221-A1 HIGH FLOW POLYSTYRENE RESINS, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2025-11-26 EP claimed
EP-4652222-A1 POLYSTYRENE FOAMS WITH A FLUOROPOLYMER ADDITIVE, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2025-11-26 EP claimed
WO-2024176037-A1 POLYSTYRENE FOAMS WITH A FLUOROPOLYMER ADDITIVE, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-08-29 WO claimed
WO-2024176035-A1 HIGH FLOW POLYSTYRENE RESINS, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-08-29 WO claimed
EP-4421115-A1 POLYSTYRENE FOAMS WITH A FLUOROPOLYMER ADDITIVE, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2024-08-28 EP claimed
EP-4421114-A1 HIGH FLOW POLYSTYRENE RESINS, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2024-08-28 EP claimed
US-11339263-B2 Fibrillated polymer compositions and methods of their manufacture SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-05-24 US claimed
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US disclosed
EP-4731711-A2 LIQUID BINDER COMPOSITIONS AND USES THEREOF Acs Technical Products, Inc. (US) 2026-04-29 EP disclosed
EP-4605473-B1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECH BV (NL) 2026-04-01 EP disclosed
EP-4305105-B1 THERMOPLASTIC COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2026-02-18 EP disclosed
EP-4244272-B1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS AND SHAPED ARTICLES THEREOF SHPP GLOBAL TECH BV (NL) 2026-02-11 EP disclosed
EP-4652221-A1 HIGH FLOW POLYSTYRENE RESINS, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2025-11-26 EP disclosed
US-11339263-B2 Fibrillated polymer compositions and methods of their manufacture SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-05-24 US disclosed
WO-2022101763-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS AND SHAPED ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-05-19 WO disclosed
EP-3004249-B1 POLYCARBONATE-SILOXANE COPOLYMER COMPOSITIONS WITH IMPROVED APPEARANCE PROPERTIES SHPP GLOBAL TECH BV (NL) 2022-04-06 EP disclosed
EP-3974412-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS Waters Technologies Corporation (US) 2022-03-30 EP disclosed
EP-3092271-B1 COMPATIBILIZED COMPOSITIONS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE THEREOF SHPP GLOBAL TECH BV (NL) 2022-03-16 EP disclosed
CN-110511550-B Polycarbonate composition, molded article comprising the same, and method for producing the article 高新特殊工程塑料全球技术有限公司 2022-02-22 CN disclosed
US-20220041839-A1 COMPOSITIONS INCLUDING A LASER MARKING ADDITIVE AND SYSTEMS AND METHODS OF LASER MARKING THE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION CYP46A1, RPTOR, PCNA KDM4E 1448/4885ALDH1A1 3743/4885HPGD 4181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.