Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11591247 | 0.83 | NQO2 (0.44) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL76177 | 0.79 | KDM4E (0.56) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL11590400 | 0.79 | RXRA (0.56) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL29377253 | 0.79 | KDM4E (0.56) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL11591420 | 0.79 | KDM4E (0.46) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| Perchlorate SCHEMBL30042407 | 0.76 | KDM4E (0.49) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL5701185 | 0.75 | CDK4 (0.41) | ALDH1A1HPGDHSD17B10DDB1CRBN | |
| SCHEMBL5871967 | 0.71 | FEN1 (0.54) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL2270324 | 0.70 | ALDH1A1 (1.00) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL2268296 | 0.67 | ALDH1A1 (0.77) | ALDH1A1HPGDHSD17B10KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103257-A | BLUE TO NEAR ULTRAVIOLET | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1978-07-25 | — | — | US | disclosed |