Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595506 | 0.86 | SMN1; SMN2 (0.66) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL11595395 | 0.84 | SMN1; SMN2 (0.53) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL11597017 | 0.82 | CA1 (0.51) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL11597707 | 0.81 | GSTO1 (0.47) | GSTO1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL11598316 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL11596069 | 0.78 | SMN1; SMN2 (0.54) | GSTO1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11596061 | 0.78 | KMT2A (0.70) | GSTO1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11595745 | 0.78 | GSTO1 (0.57) | GSTO1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9448906 | 0.76 | TSHR (0.52) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL13543287 | 0.76 | SMN1; SMN2 (0.51) | GSTO1ALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125614-A | DIURETIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-4061761-A | Thiazolidine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |