Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11597707 | 0.87 | GSTO1 (0.47) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL11598345 | 0.82 | GAA (0.44) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL11597017 | 0.80 | CA1 (0.51) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL11595561 | 0.79 | POLB (0.62) | ALDH1A1KMT2AMEN1HTTPOLB | |
| SCHEMBL11595632 | 0.79 | POLB (0.54) | ALDH1A1KMT2AMEN1HTTPOLB | |
| SCHEMBL11595105 | 0.79 | GSTO1 (0.48) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL11597183 | 0.79 | LMNA (0.51) | ALDH1A1KMT2APOLBSMN1; SMN2LMNA | |
| SCHEMBL11596763 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL11597018 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL11595506 | 0.76 | SMN1; SMN2 (0.66) | ALDH1A1KMT2AMEN1HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125614-A | DIURETIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-4061761-A | Thiazolidine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |