Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.49 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.49 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761462 | 0.89 | CYP19A1 (0.52) | GPR35ALDH1A1TDP1TSHRHIF1A | |
| SCHEMBL24616418 | 0.86 | ALDH1A1 (0.52) | GPR35ALDH1A1TDP1TSHRHIF1A | |
| SCHEMBL25422317 | 0.84 | TSHR (0.50) | GPR35ALDH1A1TDP1TSHRHIF1A | |
| SCHEMBL27850186 | 0.81 | ALDH1A1 (0.50) | GPR35ALDH1A1TDP1TSHRHIF1A | |
| SCHEMBL11644843 | 0.80 | ALDH1A1 (0.44) | GPR35ALDH1A1TDP1TSHRHIF1A | |
| SCHEMBL9788476 | 0.79 | ALDH1A1 (0.57) | GPR35ALDH1A1TDP1TSHRHIF1A | |
| SCHEMBL11452635 | 0.78 | VCAM1 (0.54) | ALDH1A1TDP1TSHRHIF1AHPGD | |
| SCHEMBL11587994 | 0.78 | ALDH1A1 (0.42) | GPR35ALDH1A1TDP1TSHRHIF1A | |
| SCHEMBL29951051 | 0.77 | ALDH1A1 (0.44) | GPR35ALDH1A1TDP1TSHRHIF1A | |
| SCHEMBL11587951 | 0.77 | GPR35 (0.40) | GPR35ALDH1A1TDP1TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117167-A | INSECTICIDES, ACARICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | disclosed |