Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644843 | 0.90 | ALDH1A1 (0.44) | CYP19A1ALDH1A1GPR35TDP1HIF1A | |
| SCHEMBL11595754 | 0.89 | GPR35 (0.56) | CYP19A1ALDH1A1GPR35TDP1HIF1A | |
| SCHEMBL9761868 | 0.85 | ALDH1A1 (0.46) | CYP19A1ALDH1A1GPR35TDP1HIF1A | |
| SCHEMBL29065983 | 0.82 | TDP1 (0.49) | CYP19A1ALDH1A1TDP1HIF1AMAPK1 | |
| SCHEMBL29065993 | 0.80 | HSPB1 (0.43) | CYP19A1ALDH1A1TDP1HIF1AKMT2A | |
| SCHEMBL12863895 | 0.80 | GPR35 (0.57) | ALDH1A1GPR35TDP1HIF1AHPGD | |
| SCHEMBL4046756 | 0.80 | ALDH1A1 (0.47) | ALDH1A1GPR35TDP1HIF1AHPGD | |
| SCHEMBL9788476 | 0.80 | ALDH1A1 (0.57) | ALDH1A1GPR35TDP1HIF1AHPGD | |
| SCHEMBL13724896 | 0.80 | CYP19A1 (0.50) | CYP19A1ALDH1A1TDP1HIF1AHPGD | |
| SCHEMBL4926322 | 0.80 | KMT2A (0.52) | CYP19A1ALDH1A1GPR35TDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990699-A | Perfluoroalkylation process | ETHYL CORPORATION (US) | 1991-02-05 | — | — | US | disclosed |