Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595465 | 0.86 | SIGMAR1 (0.43) | CYP1A2SMN1; SMN2SIGMAR1LMNAXDH | |
| SCHEMBL2303091 | 0.83 | NPC1 (0.51) | SMN1; SMN2ABL1BCRKMT2ASIGMAR1 | |
| SCHEMBL5023863 | 0.80 | SIGMAR1 (0.62) | CYP1A2SMN1; SMN2ABL1BCRKMT2A | |
| SCHEMBL29863560 | 0.79 | XDH (0.59) | ABL1BCRKMT2ALMNAXDH | |
| SCHEMBL28645698 | 0.79 | XDH (0.59) | ABL1BCRKMT2ALMNAXDH | |
| SCHEMBL23885052 | 0.78 | KMO (0.42) | SMN1; SMN2ABL1BCRPOLBLMNA | |
| SCHEMBL14636547 | 0.77 | SIGMAR1 (0.71) | SIGMAR1 | |
| SCHEMBL14635580 | 0.77 | SIGMAR1 (0.71) | SIGMAR1 | |
| SCHEMBL7919917 | 0.77 | CYP1A2 (0.39) | CYP1A2SMN1; SMN2ABL1BCRKMT2A | |
| SCHEMBL30304824 | 0.76 | SIGMAR1 (0.39) | SIGMAR1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100286-A | 2-(Substituted heterocyclic amine)benzoic acids | SCIENCE UNION ET CIE (FR) | 1978-07-11 | — | — | US | disclosed |