Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29863560 | 1.00 | XDH (0.59) | XDHABL1BCRMEN1KMT2A | |
| SCHEMBL2303091 | 0.86 | NPC1 (0.51) | XDHABL1BCRMEN1KMT2A | |
| SCHEMBL11595465 | 0.82 | SIGMAR1 (0.43) | XDHLMNAHTTSRCMAPK1 | |
| SCHEMBL24393326 | 0.80 | XDH (0.61) | XDHABL1BCRMEN1KMT2A | |
| SCHEMBL11596169 | 0.79 | CYP1A2 (0.55) | XDHABL1BCRKMT2ALMNA | |
| SCHEMBL11981833 | 0.79 | XDH (0.64) | XDHABL1BCRMEN1KMT2A | |
| SCHEMBL838709 | 0.77 | ALDH1A1 (0.64) | MEN1KMT2ALMNAGAAHTT | |
| SCHEMBL22509965 | 0.77 | XDH (0.57) | XDHABL1BCRMEN1KMT2A | |
| SCHEMBL23885052 | 0.77 | KMO (0.42) | XDHABL1BCRLMNAGAA | |
| SCHEMBL24392123 | 0.76 | XDH (0.56) | XDHABL1BCRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112826821-B | Application of allopurinol derivative in preparation of medicine for preventing and/or treating diabetes | 成都阿奇生物医药科技有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-112826821-A | Application of allopurinol derivative in preparation of medicine for preventing and/or treating diabetes | 成都阿奇生物医药科技有限公司 | 2021-05-25 | — | — | CN | disclosed |