Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.65 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856205 | 0.91 | NQO2 (0.56) | NQO2CYP2A6NR4A2PIK3R1PIK3CA | |
| SCHEMBL5157721 | 0.91 | NQO2 (0.56) | NQO2CYP2A6NR4A2PIK3R1PIK3CA | |
| SCHEMBL5157381 | 0.88 | PIK3CG (0.58) | NQO2NR4A2PIK3R1PIK3CAPIK3CG | |
| Benzo[B]Phenazine SCHEMBL5481172 | 0.80 | NQO2 (1.00) | NQO2ESR1ESR2MAPTALDH1A1 | |
| SCHEMBL13156487 | 0.80 | NQO2 (0.88) | NQO2CYP2A6ESR1ESR2MAPT | |
| SCHEMBL29581162 | 0.78 | TDP1 (0.55) | NR4A2PIK3R1PIK3CAPIK3CGMAPT | |
| SCHEMBL404069 | 0.78 | TDP1 (0.55) | NR4A2PIK3R1PIK3CAPIK3CGMAPT | |
| SCHEMBL17269519 | 0.78 | PIK3CG (0.54) | NR4A2PIK3R1PIK3CAPIK3CGMAPT | |
| SCHEMBL15196672 | 0.78 | PIK3CG (0.54) | NR4A2PIK3R1PIK3CAPIK3CGMAPT | |
| SCHEMBL13770441 | 0.78 | CHEK1 (0.47) | NQO2CYP2A6ESR1ESR2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119460-A | FUSED CARBOCYCLIC RING COMPOUNDS, POLYPHENYL COMPOUNDS NITROGEN-FREE POLYARYLATED COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1978-10-10 | — | — | US | disclosed |